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Researchers say low-dose DHEA effective for hypopituitarism.
2002 JUN 20 - (NewsRx.com & NewsRx.net) -- Researchers in Sweden have shown that low doses of dehydroepiandrosterone (DHEA) are an effective addition to the conventional treatment of women who suffer from hypopituitarism.
Results of the study are published in the May issue of the Journal of Clinical Endocrinology & Metabolism.
"DHEA was shown to improve both mental and physical conditions in the women," said Professor Anders Karlsson, chief investigator on the study and a researcher at the University Hospital, Uppsala, Sweden.
In the randomized, double-blind, placebo-controlled study, performed at the University Hospitals in Gothenburg and Uppsala, Sweden, 38 hypopituitary women with severe androgen deficiency, ages 25-65, were treated with low, age-adjusted doses of DHEA. The trial was also followed by another 6 months of open treatment, at which time any of the study's participants could choose to be treated with DHEA. The researchers studied the physical and psychological effects of the treatment, including effects on skin, hair, body composition, glucose metabolism, lipoproteins, coagulation, quality of life, and sexual interest/activity, and compared the results between the DHEA group, the placebo group, and the open treatment.
Part of the study involved quality of life questionnaires for the women and their partners. According to the women's partners, the women who took DHEA showed ...
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Source: HighBeam Research, Researchers say low-dose DHEA effective for hypopituitarism.