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<a href="http://www.accessmylibrary.com/article-1G1-87152134/test-predicts-if-chemotherapy.html" title="Facts and information about Test predicts if chemotherapy will work.(scintigraphic imaging as a test for chemotherapy resistance)(Brief Article)">Test predicts if chemotherapy will work.(scintigraphic imaging as a test for chemotherapy resistance)(Brief Article)</a>
Test predicts if chemotherapy will work.(scintigraphic imaging as a test for chemotherapy resistance)(Brief Article)
Women's Health Weekly
|
June 20, 2002 |
COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright
2002 JUN 20 - (NewsRx.com & NewsRx.net) -- Resistance to chemotherapy is a major cause of treatment failure in patients with breast cancer. A study reported in the June 2002 issue of the Journal of Nuclear Medicine found that scintigraphic imaging with [superscript]99mTc-sestamibi accurately predicted which breast tumors would be chemoresistant.
The study was able to predict 100% of the time which patients would respond to chemotherapy, and 83% of the time which patients would not respond. Physicians in this phase II clinical trial studied 30 patients with untreated locally advanced breast cancer for whom a cycle of chemotherapy followed by surgery was planned. The patients received an injection of [superscript]99mTc-sestamibi and were scanned before treatment and again before surgery.
Those who were likely to respond had a low wash-out rate, or WOR (
<45%) of the [superscript]99mTc-sestamibi. That means a higher amount of it remained in the body after injection, and showed up in the scan. Those unlikely to respond had a higher WOR (>45%). The ...
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