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Pneumoccal conjugate vaccine lowered incidence of pneumococci in children.(Brief Article)

Vaccine Weekly

| June 19, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 JUN 19 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A 9-valent pneumococcal conjugate vaccine lowered the carriage rate of pneumococci among children in day care centers, researchers in Israel found.

R. Dagan and colleagues at the Pediatric Infectious Disease Unit of Soroka University in Israel performed a double-blind randomized trial involving 264 children in day care centers "to document the effect of a 9-valent pneumococcal vaccine on the carriage rate of pneumococci," according to the authors.

Two years after inoculating the treatment group, Dagan and associates analyzed the results obtained from evaluation of the 3750 nasopharyngeal samples taken from the toddlers.

Sixty-five percent of the samples proved positive for Streptococcus pneumoniae, with a lower carriage rate among vaccinated children than among children in the control group. The carriage rate was even lower in children age 36 months or younger. Dagan and coworkers reported that a lower acquisition rate was responsible for the lower incidence. (Reduction of nasopharyngeal carriage of Streptococcus pneumoniae after administration of a 9-valent pneumococcal conjugate vaccine to toddlers attending daycare centers, Journal of Infectious Diseases, 2002;185(7):927-936)

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Source: HighBeam Research, Pneumoccal conjugate vaccine lowered incidence of pneumococci in...

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