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Vitamin K-2 prevents bone loss in women with cirrhosis.(Brief Article)
2002 JUN 13 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Women diagnosed with cirrhosis may be able to avoid bone loss by taking vitamin K-2 supplements, doctors say.
A report issued by physicians at Osaka City University School of Medicine in Japan provides new information that should lessen the debate about whether or not osteoporotic therapy might be beneficial for women with cirrhosis. Liver diseases such as cirrhosis are known to cause bone loss, and due to hormonal changes, females are at particular risk for developing osteoporosis as they grow older.
In a new study, S. Shiomi and colleagues compared bone mineral densities (BMD) among 50 women with cirrhosis who were randomized to receive vitamin K-2 supplementation or no therapy. All of the women had viral hepatitis, researchers said.
"The percentages of change from the initial BMD at 1 and 2 years after initiation of the study were, respectively, +0.1 [plus-or-minus sign] 2.6% and -0.5 [plus-or-minus sign] 3.5% for the vitamin K-2-treated group and -2.2 [plus-or-minus sign] 2.4% and -4.6 [plus-or-minus sign] 3.9% for the control group," Shiomi and coauthors noted.
Researchers also checked the women for levels of osteocalcin, a protein produced by bone cells that modulates bone mineral ...
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Source: HighBeam Research, Vitamin K-2 prevents bone loss in women with cirrhosis.(Brief Article)