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Single rotavirus genotype linked to gastroenteritis outbreaks.(Brief Article)
2002 MAY 29 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A single, distinctive type of rotavirus may be responsible for the vast majority of rotavirus-induced gastroenteritis, researchers report.
Dr. Dixie D. Griffin and colleagues at the U.S. Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia, the District of Columbia Department of Health in Washington, DC, the State of Hawaii Department of Health in Pearl City, the Maryland State Department of Health and Mental Hygiene in Baltimore, and the Hale Ola Kino Skilled Nursing Facility in Honolulu, Hawaii, examined the causal factors behind gastroenteritis outbreaks in the United States.
One rotavirus serotype was implicated in all outbreaks caused by rotavirus infections, a finding that should be taken into account by rotavirus vaccine developers, Griffin and coauthors said.
Specimens taken from patients afflicted during more than 260 gastroenteritis outbreaks in the late 1990s were examined at the CDC. Three of these outbreaks were ultimately linked to rotavirus infection, the researchers found.
All isolates from these three outbreaks were rotaviruses of the G2 serotype, according to the report. This serotype, "genetically distinct in all 11 gene segments from the other common rotavirus strains in circulation," has also been linked ...
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