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2002 MAY 16 - (NewsRx.com & NewsRx.net) -- New data with longer follow-up from four Swedish trials published in the Lancet (2002;359(9310):904-905) suggest there may be a modest benefit from screening mammography for women age 55 years or over.
Considerable debate surrounds the issue of screening mammography and its possible benefits. A research letter by Ole Olsen and Peter Gotzsche (Lancet, 2001;358:1340-1342) concluded that there was no reliable evidence from randomized trials to support the benefit of screening mammography. Lennarth Nystrom and colleagues from the University of Umea, Sweden, presented new data updating the overview of four Swedish randomized controlled trials on mammography screening up to and including 1996. The study also contains data from the trials that have not been presented before.
The trials include data for about 247,000 women, who were followed up by record linkage to the Swedish Cancer and Cause of Death Registers. The relative risks for breast cancer death and death from all causes were calculated for women given screening mammography and those not invited for screening (the control groups in the four trials).
Average follow-up time for the trials was 15.8 years. There were 511 breast cancer deaths in 1,864,770 women-years in the groups given mammography, and 584 breast cancer deaths in 1,688,440 women-years in the control groups - resulting in a significant 21% reduction in breast cancer mortality for women given screening mammography. The reduction was greatest (33%) in the age group 60-69 years at ...
Source: HighBeam Research, Swedish trials suggest modest benefit for screening...