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Statin use may protect against cognitive impairment.(Brief Article)
2002 APR 11 - (NewsRx.com & NewsRx.net) -- Women with high levels of serum lipoprotein (high-density lipoprotein and low-density lipoprotein [LDL]) and no dementia are at higher risk of developing cognitive impairment than women who have lower lipoprotein levels and who are on statin drugs, according to an article in the March 14, 2002, issue of the Archives of Neurology.
Kristine Yaffe, MD, from the University of California, San Francisco, and colleagues studied 1037 postmenopausal women younger than 80 years with established coronary disease from the Heart Estrogen/progestin Replacement Study Trial. None of the women had a history of dementia at enrollment. Participants were randomly assigned to treatment with daily oral estrogens or placebo.
The Modified Mini-Mental State Examination (3MS, a brief cognitive test) was administered at the end of the 4-year trial.
"High LDL and total cholesterol levels are associated with cognitive impairment," the authors stated. "Lowering these lipoprotein levels may be a strategy for preventing impairment."
In background information in the article, the authors noted that few modifiable risk factors for cognitive impairment have been identified. Certain studies, according to the authors, suggest that high total cholesterol levels ...
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ATLANTA -- Variations in lipoprotein (a) levels appear to explain the early risk for cardiovascular events observed in the Heart and Estrogen/Progestin Replacement Study, Dr. Michael G. Shlipak reported at the annual scientific sessions of the American Heart Association. His new subgroup analysis
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- Magazine article from: Alternative Medicine Review August 1, 2000 700+ words
Tamoxifen, a non-steroidal antiestrogen, has been used in the hormonal treatment for breast cancer. The hepatic estrogenic effect of tamoxifen causes severe triglyceridemia. The combined effect of tamoxifen, vitamin C and vitamin E on plasma lipid and lipoprotein is important, since, vitamin C and
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- Magazine article from: Canadian Medical Association. Journal Chertkow, Howard; Massoud, Fadi; Nasreddine, Ziad; Belleville, Sylvie; Joanette, Yves; Bocti, Christian; Drolet, Valérie; Kirk, John; Freedman, Morris; Bergman, Howard May 6, 2008 700+ words
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- News wire article from: AScribe Health News Service April 4, 2006 700+ words
...researchers have found that mild cognitive impairment, a disorder considered a strong...not have dementia might have mild cognitive impairment. To date, 1,116 people without...Olmsted County, Minn., have mild cognitive impairment. The prevalence of mild cognitive...
