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Group suspects curcumin suppresses breast cancer in number of ways.(Brief Article)
2002 APR 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - New research suggests curcumin, also known as tumeric yellow, exerts pressure on human breast cancer cells by means of several different mechanisms.
Curcumin has undergone scientific evaluation for its anticancer properties for several years now, particularly in Asian countries. A joint investigation by researchers in the U.S. and China has shed new light on the ways in which curcumin inhibits cell growth and invasion in estrogen receptor-positive (ER[superscript]+) and -negative (ER[superscript]-) breast cancers.
The investigation involved breast cancer cells cultured in the laboratory. According to Zhi-Ming Shao, an investigator working at both the University of California - Los Angeles School of Medicine and Fudan University Medical Center in Shanghai, People's Republic of China, curcumin arrested the proliferation of ER[superscript]+ breast cancer cells, with the presence of exogenous estrogen augmenting that suppression. Curcumin also influenced gene signals in ER[superscript]+ cells.
Moreover, curcumin weakened invasion by breast cancer cells that were ER[superscript]-, according to Shao and coauthors. To do that, curcumin targeted two extracellular factors associated with cancer invasion, causing matrix metalloproteinase (MMP)-2 ...
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Source: HighBeam Research, Group suspects curcumin suppresses breast cancer in number of...