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Simian virus found in human lymphoma samples.(Brief Article)
2002 APR 3 - (NewsRx.com & NewsRx.net) -- Evidence of simian virus 40 (SV40) infection found in 42% of non-Hodgkin lymphoma samples could shed new light on the genesis of these blood cancers that have become more common over the past 30 years, said Baylor College of Medicine scientists in a report in the March 9, 2002, issue of the Lancet. About 55,000 new cases of the disease are diagnosed annually.
"This is an important finding because cancers with a viral cause offer the possibility of developing new and better ways of treating and diagnosing and ultimately preventing the tumor," said Dr. Janet Butel, chairman of the department of molecular virology and microbiology at Baylor and senior author of the report.
"This study further demonstrates that humans can be infected by SV40, an infection that was not suspected in the past," she said. SV40 usually infects rhesus monkeys. However, in the 1950s and early 1960s, some batches of polio vaccine became accidentally infected with the virus. The vaccine was ...
- Pleural mesothelioma incidence not related to SV40-contaminated polio...
- Newspaper article from: Cancer Weekly March 4, 2003 700+ words
...polio with vaccines contaminated with simian virus 40 do not appear to have an increased...and early 1960s were contaminated with simian virus 40 (SV40), a monkey virus that is...mesothelioma incidence rates following simian virus 40 contamination of early poliovirus...
- Study examines simian virus 40 T-antigen double hexamers in helicase.(Brief...
- Newspaper article from: Virus Weekly January 28, 2003 700+ words
...viral helicase required for the initiation and elongation of simian virus 40 DNA replication. The unwinding activity of the helicase...in Journal of Biological Chemistry (Characterization of simian virus 40 T-antigen double hexamers bound to a replication fork...
- Association found between simian virus 40 and non-Hodgkin lymphoma.
- Newspaper article from: Cancer Weekly March 23, 2004 700+ words
...amp; NewsRx.net) -- An association exists between simian virus 40 (SV40) and non-Hodgkin lymphoma. According to recent...Millions of people worldwide were inadvertently exposed to live simian virus 40 between 1955 and 1963 through immunization with SV40...
- The detection of Simian virus 40 in mesotheliomas from New Zealand and England...
- Magazine article from: Journal of Clinical Pathology Mayall, F. Barratt, K. Shanks, J. October 1, 2003 700+ words
...Clin Pathol 2003;56:728-730 Aims: To detect Simian virus 40 (SV40) DNA in mesotheliomas from New Zealand and...mesotheliomas. ********** The detection of Simian virus 40 (SV40) DNA in mesotheliomas was first reported...
- Human lymphocytes not susceptible to simian virus 40 infection.
- Newspaper article from: Biotech Week June 16, 2004 700+ words
...Chicago, "[l]ymphoblastic cell lines were infected with simian virus 40 (SV40) and then monitored for evidence of a productive...published their study in the Journal of Virology (Inability of simian virus 40 to establish productive infection of lymphoblastic cell...
- Crystal structure solves virus puzzle. (simian virus 40)
- Magazine article from: Science News Pennisi, Elizabeth December 7, 1991 700+ words
...used synchrotron radiation to probe the crystal structure of simian virus 40, a cousin of the papillomavirus that causes warts in...describe how the five-sided bundles link up. The coat on simian virus 40 contains a total of 360 proteins. Each proten consists...
- Simian virus 40, poliovirus vaccines, and human cancer: research progress...
- Magazine article from: Bulletin of the World Health Organization Butel, J.S. February 1, 2000 700+ words
Simian virus 40 (SV40) is a polyomavirus of rhesus macaque origin (1-3). It was present but unrecognized in the monkey kidney cell cultures...
- Simian virus 40 and human malignancy: contamination of early polio vaccine may...
- Magazine article from: British Medical Journal Stenton, S.C. March 21, 1998 700+ words
...contaminating virus was identified in the rhesus monkey kidney cells that were used to culture the poliovirus. It was named simian virus 40 (SV40). It was more resistant than poliovirus to chemical denaturation and survived into some vaccine samples. There...
- No Role for Simian Virus 40 in Human Pleural Mesotheliomas; Assays for SV40 DNA...
- News wire article from: Ascribe Higher Education News Service September 23, 2004 700+ words
...Seventy to eighty percent of patients with this rare cancer have had exposure to asbestos. It has also been proposed that simian virus 40 (SV40), a contaminant in some polio vaccines administered in the 1950's and 1960's, might be a cause. However...
- SV-40 in non-Hodgkins lymphoma. (Updates).(simian virus 40)
- Magazine article from: Infectious Disease Alert Kemper, Carol A. April 1, 2002 700+ words
...Vilchez R, et al. Lancet. 2002;359:817-823; Shivapurkar N, et al. Lancet. 2002;359:851-852. THE ROLE OF SIMIAN VIRUS 40 (sv-40) in the development of "soft cell" cancers, such as sarcomas, certain lung and brain cancers, and lymphoma...
Source: HighBeam Research, Simian virus found in human lymphoma samples.(Brief Article)