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The European Collaborative Study. Fluctuations in symptoms in human immunodeficiency virus-infected children: the first 10 years of life. Pediatrics 2001 Ju1;108:116-22.
QUESTION: in children with HIV infection at birth, who received differing treatment protocols, what are the clinical and immunological manifestations during the first 10 years of life?
Design
Cohort study with a median of 5.8 years of follow up.
Setting
11 paediatric centres in 7 European countries.
Patients
170 HIV infected children who were born to mothers known to be infected with HIV at the time of delivery.
Assessment of prognostic factors
Children were categorised into 3 cohorts according to the treatment policy at the time of birth. Cohort 1 consisted of children born from …