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2002 FEB 14 - (NewsRx.com & NewsRx.net) -- Fertility drugs do not put women at a higher than average risk of ovarian cancer, according to the largest analysis to date on the topic.
The study, conducted by University of Pittsburgh Graduate School of Public Health (GSPH) researchers, was published in the February 1, 2002, issue of the American Journal of Epidemiology.
"For more than a decade, controversy has surrounded the relationships among infertility, fertility drug use, and the risk of ovarian cancer," said Roberta Ness, MD, MPH, associate professor of epidemiology at GSPH and principal investigator on the study. "This analysis helps put to rest the questions that have been troubling physicians and the women who endure arduous fertility treatments."
While no association was found between ovarian cancer and fertility drugs, the study does point out a link between ovarian cancer and certain specific causes of infertility - namely, endometriosis and "unknown" reasons for infertility. The study suggests that some women who receive fertility treatments develop ovarian cancer because of underlying conditions that cause infertility, not because of the treatments themselves.
Investigators collected interview data on infertility and fertility drug use from eight case-control studies conducted between 1989 and 1999 in the United States, Denmark, Canada, and Australia, including 5207 women with ovarian cancer, and 7705 women without ovarian cancer. In the study, infertility was signaled by prolonged unsuccessful episodes of trying to conceive, and by seeking medical help in conceiving.
Results showed that women who spent more than 5 years trying to conceive were at a 2.7-fold higher risk for ovarian cancer than those who tried for ...
Source: HighBeam Research, Study Finds No Association Between Fertility Drugs And Disease...