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Vical's Naked DNA Technology Used To Deliver HIV Vaccine.(Brief Article)
2002 FEB 13 - (NewsRx.com & NewsRx.net) -- A new study published in Nature describes the use of the Vical, Inc., (VICL) "naked DNA" technology in the ongoing efforts to develop a vaccine to combat human immunodeficiency virus (HIV).
The report in Nature described studies conducted by Merck & Co., Inc., including a study in which a vaccine regimen employing Vical's patented naked DNA nonviral gene delivery technology was used in a prime-boost regimen with naked DNA plus adjuvant to prime and Merck's nonreplicating adenoviral vector to boost. This vaccine combination was shown to provide potent cellular immune responses to a hybrid form of HIV that can replicate and cause clinical disease in monkeys.
"This early stage animal research is part of ongoing studies to determine the role for Vical's naked DNA technology used in ...
- Merck Confirms Use of Vical's Naked DNA Technology in HIV Vaccine Program.
- Press release article from: PR Newswire April 2, 2001 700+ words
...serious disease. We are pleased that our naked DNA technology has contributed to their success and...associated viruses with Vical's naked DNA technology in the prime vaccine. The naked DNA technology has demonstrated the ability to induce...
- New Research Includes Use of Vical's 'Naked DNA' Technology for HIV Vaccine.
- Press release article from: PR Newswire January 18, 2002 700+ words
...the Vical Incorporated "naked DNA" technology in the ongoing efforts to...determine the role for Vical's naked DNA technology used in combination with...founded." Merck is using naked DNA technology as a component of its efforts...
- Merck Licenses Vical's "Naked" DNA Technology to Deliver Certain Growth Factors.
- Press release article from: Business Wire September 15, 1997 700+ words
...rights to use Vical's "naked" DNA technology to deliver certain growth...options to license Vical's naked DNA technology to deliver growth factors...first license of Vical's naked DNA technology for potential delivery of...
- Vical Licenses Naked DNA Technology to Aventis Pharma for Growth Factor...
- Press release article from: Business Wire July 6, 2000 700+ words
...NYSE:AVE), rights to use Vical's naked DNA gene transfer technology to deliver a...for which Aventis Pharma holds rights. Naked DNA is Vical's patented method for delivering...commercialization. Several companies have tested naked DNA delivery of angiogenic growth factor...
- Vical Discloses Preclinical Data On Naked DNA Vaccine for Prostate Cancer.
- Press release article from: Business Wire April 4, 2000 700+ words
...vaccine using the company's patented naked DNA gene delivery technology. Naked DNA technology has been used widely in the development...current research Vical scientists used the naked DNA technology to deliver a prostate cancer antigen...
- MERCK EXERCISES REMAINING NAKED DNA VACCINE OPTIONS.
- Press release article from: Business Wire May 1, 1995 700+ words
...three options to license Vical's proprietary naked DNA vaccine technology for development of vaccines...worldwide, to develop veterinary vaccines based on naked DNA technology. Naked DNA vaccines may prove superior to conventional vaccines...
- Vical Presents Naked DNA Enhancement Technologies; New Methods to Boost...
- Press release article from: Business Wire June 4, 2000 700+ words
...DNA gene delivery compared with naked DNA gene delivery alone. Vical's...collaborators and on a contract basis. Naked DNA Technology The key discovery leading to Vical's patented naked DNA direct gene delivery technology...
- Vical Presents Preclinical Data On Novel Naked DNA Cancer Therapy.
- Press release article from: Business Wire November 18, 1998 700+ words
...the company's patented naked DNA technology to deliver circulating therapeutic...additional potential for Vical's naked DNA technology not only for IFN(alpha...candidates based on its patented naked DNA technology. A number of therapeutic...
- Vical to Receive $1 Million Milestone Payment; Merck Initiates Naked DNA HIV...
- Press release article from: Business Wire January 7, 2000 700+ words
...Phase I clinical trial testing a naked DNA vaccine to prevent infection with...vaccine using Vical's patented naked DNA gene delivery technology. The...holds a license to use Vical's naked DNA technology for a therapeutic vaccine against...
- Vical to Begin Collaborative Naked DNA Safety and Efficacy Vaccine Trial for...
- Press release article from: Business Wire August 22, 2000 700+ words
...include dose escalation of a naked DNA agent encoding granulocyte macrophage...Vical for development work on a naked DNA vaccine to prevent malaria...advantages in safety and efficacy. Naked DNA Technology A typical human cell contains...
Source: HighBeam Research, Vical's Naked DNA Technology Used To Deliver HIV Vaccine.(Brief...