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First Consensus Opinion On Risk Management With Ductal Lavage Published.

Women's Health Weekly

| February 07, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2002 FEB 7 - (NewsRx.com & NewsRx.net) -- Two oncologists at Baylor University Medical Center (BUMC), Dallas, Texas, published the first guidelines on the use of ductal lavage to help manage high-risk breast cancer.

The guidelines were coauthored by Joyce O'Shaughnessy, MD, medical oncologist and director of breast cancer prevention on the medical staff at BUMC and U.S. Oncology, and Michael Grant, MD, surgical oncologist on the medical staff at BUMC. The consensus statement also reviews data supporting breast duct cytology as a tool for providing women with biological information about their personal risk of developing breast cancer.

Ductal lavage is a minimally invasive procedure that is used to collect breast ductal cells for analysis. This procedure is performed on women who are considered to have a higher-than-normal risk of developing the disease. More than 95% of breast cancers begin in the cells lining the milk duct system and many begin as normal cells that can eventually become malignant. Ductal lavage can be performed during an office visit and is less invasive than a fine needle aspiration and many women report that it is less uncomfortable than a mammogram.

The consensus was published in the January 2002 issue of the journal Cancer (Ductal Lavage and the Clinical Management of Women at High Risk for Breast Carcinoma, Cancer, 2002;94(2):292-298).

Physicians and patients use the results from ductal lavage to weigh the risks and benefits of a variety of management options ranging from or including closer surveillance, hormone replacement therapy, antiestrogen therapy (tamoxifen), and in very high-risk women, even prophylactic mastectomy.

"Data supporting ductal lavage indicates it is an effective tool for providing women with individualized information regarding their risk of developing breast cancer," said O'Shaughnessy. "With ductal lavage having achieved significant adoption by physicians since its commercial introduction in late 2000, clinicians were in need of guidelines regarding the interpretation and use of breast ductal cytology to guide risk reduction management strategies in their high-risk patients. Our guidelines were written to address that need."

Ductal lavage is a unique tool that will help further evaluate women who may be at an elevated risk for developing breast cancer.

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