AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
DNA Vaccine Expressing Human Papillomavirus Gene Invites Viral Immunity.(Brief Article)
2002 FEB 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - An experimental vaccine containing genes for the human papillomavirus 16-L1 (HPV16-L1) protein has shown promising results for halting tumor growth and extending survival in mice.
Researchers say that the plasmid DNA vaccine might be effective for preventing human HPV16 infection, a disease associated with the formation of cervical cancer in women.
According to Leticia Rocha-Zavaleta and associates at the Universidad Nacional Autonoma de Mexcio, Mexico City, the plasmid DNA vaccine worked well when administered either orally, subcutaneously, or intramuscularly to mice, generating sizeable numbers of IgG antibodies against L1.
"Antibodies developed in mice vaccinated subcutaneously were detectable 12 months postimmunization," Rocha-Zavaleta and coworkers stated.
Because HPV infection is a significant risk factor for cervical cancer, researchers were particularly interested in finding out whether antibodies induced by the vaccine could be detected in gynecological tissues. Vaginal washes from immunized mice contained IgA antibodies specific to the viral antigen, according to the investigators.
In challenge experiments where ...
- Human papillomavirus vaccine recombinant quadrivalent: First report of...
- Magazine article from: Reactions Weekly Anonymous October 11, 2008 700+ words
...receiving recombinant quadrivalent human papillomavirus vaccine [Gardasil]. The woman...doses of IM recombinant quadrivalent human papillomavirus vaccine [dosage not stated] into...her first recombinant quadrivalent human papillomavirus vaccine dose. Physical examination...
- New human papillomavirus study findings reported from E.Q. Wu and co-authors.
- Newspaper article from: Cancer Weekly September 1, 2009 700+ words
...Journal of Gynecological Cancer, "Human papillomavirus (HPV) is the main etiologic factor...in HSIL, and 63.4% in LSIL. Human papillomavirus 16 was the most predominant HPV...of HSIL, and 33.8% of LSIL. Human papillomavirus 45 was the second most predominant...
- Investigators at Karolinska University zero in on human papillomavirus.
- Magazine article from: Women's Health Weekly August 20, 2009 700+ words
...conducted a study "To assess the use of human papillomavirus genotyping in cervical intraepithelial...underwent cytologic testing and human papillomavirus genotyping at the follow-up visit...of high-/intermediate-risk human papillomavirus types predicted 100% of residual...
- Virus-like particles do not activate Langerhans cells.(human papillomavirus)
- Magazine article from: Women's Health Weekly December 5, 2002 700+ words
...Langerhans cells are not activated by human papillomavirus (HPV) virus-like particles...including cervical cancer. Because human papillomavirus-infected women do not always mount...we explored the interaction of human papillomavirus with Langerhans cells, which would...
- Reports summarize human papillomavirus research from L. Licitra and...
- Newspaper article from: Blood Weekly February 12, 2009 700+ words
...assess incidence and survival of human papillomavirus-related and unrelated head and...Milan, Italy report (see also Human Papillomavirus). "This analysis was performed...the period from 1988 to 2002. The human papillomavirus-unrelated cancer sites had an...
- Researchers from Karolinska University, Karolinska Institute detail findings in...
- Newspaper article from: Cancer Weekly August 11, 2009 700+ words
...Sweden, "To define the spectrum of human papillomavirus (HPV) types and establish an age...Switzerland)." "High-risk human papillomavirus (HR-HPV) was found in 71% of...p <0.001). High-risk human papillomavirus prevalence was age-dependent in...
- Human papillomavirus vaccine recombinant quadrivalent: Palpitations, dizziness,...
- Magazine article from: Reactions Weekly Anonymous October 18, 2008 700+ words
...receiving recombinant quadrivalent human papillomavirus vaccine [dosages not stated...received recombinant quadrivalent human papillomavirus vaccine at their school, presented...doses of recombinant quadrivalent human papillomavirus vaccine and did not develop any...
- Scientists at Capital Medical University target human papillomavirus.(Survey)
- Newspaper article from: Cancer Vaccine Week November 16, 2009 700+ words
Data detailed in 'Human papillomavirus infection in Beijing, People...No recent data exist on human papillomavirus (HPV) infection in Beijing...China report (see also Human Papillomavirus). "Cervical cell samples...
Source: HighBeam Research, DNA Vaccine Expressing Human Papillomavirus Gene Invites Viral...