AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
CancerVax Submits IND Application for Canvaxin.(Brief Article)
2002 JAN 30 - (NewsRx.com & NewsRx.net) -- CancerVax Corp. has submitted an Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) to initiate a pivotal (Phase II/III) clinical trial of the Canvaxin therapeutic cancer vaccine as a treatment for metastatic colon cancer.
"We are very pleased with the achievement of this important milestone for CancerVax," said David F. Hale, president and chief executive officer. "There is a significant need for more effective and safer therapeutics for the treatment of advanced metastatic colon cancer, which is one of the deadliest forms of cancer in the U.S. and the world. With the start of this pivotal trial, following FDA review of the protocol, Canvaxin will be in late-stage, multicenter clinical trials for two cancers for which there are currently no adequate therapies - advanced metastatic colon cancer and metastatic melanoma."
The Canvaxin vaccine, CancerVax's lead product candidate, is an allogeneic whole-cell vaccine that expresses at least 20 known tumor-associated antigens, 14 of which are specifically cross-reactive with colon cancer, which the company believes enhances overall immune response to the cancer. Unlike ...
- Cancer Immunotherapy: "Expression of Signal Transducing T-Cell Receptor zeta...
- Newspaper article from: Immunotherapy Weekly November 9, 1998 700+ words
...gastric (n=11) and colon (n=3) cancer with stage IV and investigated whether the alteration of signal...lymphocytes (PBL) of patients with gastric and colon cancer with stage IV compared to healthy donors (n=15). AIT induced...
- CancerVax(TM) Submits IND Application to FDA for the Canvaxin(TM) Vaccine In...
- Press release article from: PR Newswire January 4, 2002 700+ words
...reactive with colon cancer, which the Company...patients with Stage IV colorectal carcinoma...patients with Stage IV colon cancer following surgical...diagnosed with colon cancer in 2001, with...Stage III and Stage IV melanoma. Advanced...
- Colon cancer vaccine study begins in Savannah next month.
- Newspaper article from: Savannah Morning News (Savannah, GA) June 14, 2006 700+ words
...help reduce the recurrence of colon cancer. The vaccine trains a patient's immune system to attack colon cancer cells. "This is unprecedented...for patients in Stage III or Stage IV of colon cancer, but surgery is the only standard...
- Intracel and FDA Agree on Pivotal Phase III Clinical Protocol for Colon Cancer...
- Press release article from: Business Wire April 27, 2006 700+ words
...need in patients with Stage II colon cancer, an earlier stage than most...Phase III clinical trial." Colon cancer is one of the most prevalent...adjuvant treatment of Stage III and Stage IV colon cancer, but none are available for...
- New 'Targeted' Treatments Improve Colon Cancer Survival Rates.
- Press release article from: PR Newswire April 3, 2007 700+ words
...to Snow's diagnosis just a few days ago of Stage IV (advanced) colon cancer. The reason that statement can be made today...the chemotherapy regimens most often used in Stage IV colon cancer. Doing so is more effective than using the...
- New findings reported from Georg-August University describe advances in colon...
- Newspaper article from: Cancer Weekly September 15, 2009 700+ words
...curatively resectable stage IV disease," scientists...report (see also Colon Cancer). "20 patients...in advanced UICC stage IV CRC.." Cameron...and asymptomatic stage IV colorectal cancer...Chemotherapy, Colon Cancer, Colon Carcinoma...
- Measuring a specific immune response may aid in diagnosis.(colon cancer)
- Newspaper article from: Cancer Weekly August 20, 2002 700+ words
...more of the 13 specific colon cancer antigens, with the most...patients with stage I colon cancer had an immune response...while more than 50% with stage IV disease did. The team also found groupings of colon cancer antigens that may turn...
- Scientists at Jikei University, Medical Department target colon cancer.
- Newspaper article from: Cancer Weekly September 1, 2009 700+ words
...stage IIIb in 6 and stage IV in 9) was perfomed...report (see also Colon Cancer). "The 5-year...III and 12% for stage IV). When compared...be regarded as a stage IV disease, for which...Cancer Research, Colon Cancer, Colon Carcinoma...