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Clinical Study Based On ESO-1 Tumor-Associated Antigen Initiated.(Brief Article)
2002 JAN 23 - (NewsRx.com & NewsRx.net) -- The Ludwig Institute for Cancer Research has initiated the first European Phase I trial for Therion Biologics' two-component vaccine targeting the tumor antigen NY-ESO-1.
In this study, the Ludwig Institute will evaluate the safety and potential activity of Therion's pox virus-based vaccine for enhancing the body's own immune response against cancer. This initial clinical study will include patients with a wide variety of ESO-expressing tumors, including breast and bladder cancer, melanoma and some sarcoma patients.
"The Ludwig Institute's efforts are dedicated to turning leading-edge science into novel treatments for a variety of cancers," said Lloyd J. Old, Ludwig Institute for Cancer Research. "As the first product from our joint research efforts with Therion enters the clinic, we recognize and look forward to other milestones in this collaboration."
"This exciting transnational collaboration allows us to rapidly evaluate the potential benefits of NY-ESO-1 immunotherapy in cancer patients," said Dennis Panicali, PhD, Therion Biologics Corporation. "To date, Therion's prime-boost approach to developing cancer vaccines has shown exciting and promising results in clinical trials for both prostate and colorectal cancer. Working with scientists from the Ludwig Institute in this trial offers an opportunity to further demonstrate the broad utility of our vaccine products for ...
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Source: HighBeam Research, Clinical Study Based On ESO-1 Tumor-Associated Antigen...