AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Second Phase II Clinical Trial Of MVA-HPV-IL2 Vaccine Initiated.(for the treatment of vulvar intraepithelial neoplasia)
2002 JAN 17 - (NewsRx.com & NewsRx.net) -- Transgene announced the initiation of a Phase II clinical trial of its immunotherapeutic MVA-HPV-IL2 vaccine candidate for the treatment of vulvar intraepithelial neoplasia (VIN3).
The trial will be conducted in France and will include up to 30 women with VIN3. VIN3 is the most severe of three different forms of vulvar intraepithelial neoplasia (VIN), a vulvar tissue disease. It is caused by changes in the cells of the tissue that allow them to grow abnormally. In a small number of cases, VIN can progress to invasive cancer of the vulva.
Current treatments are usually irritating to patients and relapse is frequent. Surgery is currently not used to treat VIN3 when the lesions are extensive.
The Phase II clinical trial will be conducted at two sites in France, Ambroise Pare Hospital in Boulogne, and Cochin Hospital in Paris, and will evaluate the efficacy of multiple subcutaneous injections. The trial will be placebo-controlled and the primary objective is to demonstrate clinical efficacy as measured by the elimination of lesions in at least half of the treated patients at six months.
"If efficacy is demonstrated in the Phase II clinical trial, we will seek orphan drug status for this indication in order to make the ...
- Third Wave's HPV Clinical Trial Achieves Primary Clinical Endpoints.
- Press release article from: Business Wire March 11, 2008 700+ words
...established by the ALTS clinical trial, the foundational HPV screening study sponsored...Third Wave initiated its HPV clinical trial two years ago, in early...Third Wave believes that an HPV clinical trial is a highly complex undertaking...
- Third Wave Begins Clinical Trial for HPV Products.
- Press release article from: PR Newswire August 7, 2006 700+ words
...announced that the clinical trial for its two...papillomavirus, or HPV, products is...pleased to be a clinical trial site for Third Wave's HPV products...complete the clinical trial on time and...believe our HPV products can...
- Clinical Trial Results Support Adoption of HPV Testing.
- Press release article from: PR Newswire July 28, 2000 700+ words
...Barcelona, Spain. The clinical trial results that were presented support the use of HPV testing as a new method...Hybrid Capture(R) HPV Test was used in the...States of America. The clinical trial in the Netherlands was based on the GP 5+/6+ HPV test developed by the...
- Transgene Initiates Third Phase II Clinical Trial Of MVA-HPV-IL2 Vaccine...
- Press release article from: PR Newswire February 28, 2002 700+ words
...initiation of a Phase II clinical trial of its immunotherapeutic MVA-HPV-IL2 vaccine candidate...million women have HPV cervical infections...abnormalities. The Phase II clinical trial will be conducted...weeks. "This new clinical trial demonstrates our...evaluating our ...
- Transgene Initiates Phase II Clinical Trial With Its MVA-HPV-IL2 Product for...
- Press release article from: PR Newswire October 18, 2001 700+ words
...initiation of a Phase II clinical trial of its immunotherapeutic MVA-HPV-IL2 product candidate...varying stages of HPV 16 cervical cancer...radiotherapy. The Phase II clinical trial will be conducted...development of our HPV program. After...from the Phase I clinical ...
- MVA-HPV-IL2 vaccine shows activity in phase II HPV clinical trial.
- Newspaper article from: Biotech Business Week April 12, 2004 700+ words
...encouraging results from the phase II clinical trial of its MVA-HPV-IL2 vaccine candidate in patients...eliminate spontaneously their HPV infection. A phase II clinical trial has been ongoing in France with MVA-HPV-IL2, which includes up to...
- Transgene's MVA-HPV-IL2 Vaccine Shows Activity in Phase II Clinical Trial.
- Press release article from: PR Newswire March 18, 2004 700+ words
...encouraging results from the phase II clinical trial of its MVA-HPV-IL2 vaccine candidate in patients...eliminate spontaneously their HPV infection. A phase II clinical trial has been ongoing in France with MVA-HPV-IL2, which includes up to...
- SeqWright's Clinical Trial Support Contributes to the Approval of Two HPV...
- Magazine article from: Women's Health Weekly April 23, 2009 700+ words
...their Cervista HPV HR clinical trial involved over...implement Hologic's HPV genotyping analysis...create a customized clinical trial decision tree...Biotechnology Company, Clinical Trial Research, DNA...Diagnostics, FDA, HPV, Human Papillomavirus...