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Mosquito-Borne Malady May Be Made More Deadly.(Brief Article)
2002 JAN 9 - (NewsRx.com & NewsRx.net) -- A new study claims that some future malaria vaccines that don't entirely wipe out the disease might unintentionally serve to make it more deadly.
The study uses mathematical analysis to examine the effect of partially effective, or "imperfect," malaria vaccines. In some scenarios, the study says, a hypothetical vaccine designed to reduce the growth rate or transmission of the malarial parasite caused it to evolve into a more virulent strain.
"The thrust of our paper is that they (parasites) can become more nasty, and certain types of vaccines can promote the nastiness of the disease," said Andrew Read, a researcher at the Institute of Cell, Animal and Population Biology at the University of Edinburgh in England. On the other hand, vaccines specifically designed to block infection resulted in less virulent strains.
The researchers examined malaria because it provides a good example of a disease likely to require "imperfect" vaccines, Read said in the article published ...
- EU/AFRICA: EURO 7 MILLION TO DEVELOP MALARIA VACCINES.(European Union)(Brief...
- Newspaper article from: European Report December 13, 2003 700+ words
The European Union has agreed a Euro 7 million grant to help develop malaria vaccines and their multi-centre trials in sub-Saharan Africa. Malaria accounts for 500 million cases and 2-3 million deaths a year...
- HEALTH RESEARCH: NEW EUROPEAN MALARIA VACCINES REACH CLINICAL TESTING...
- Newspaper article from: European Report January 13, 2001 700+ words
...for controlling this disease. Already serious, the situation is deteriorating rapidly. Since 1985, several candidate malaria vaccines have entered clinical evaluation. Over 80 trials have been conducted. Unfortunately, none of the candidates have shown...
- Malaria vaccines could lead to more malaria deaths, study says.(Brief Article)
- Newspaper article from: BioWorld International Kingman, Sharon December 19, 2001 700+ words
LONDON -- Vaccines that are not completely effective could do more harm than good, a mathematical model developed by population biologists suggests. By allowing pathogens that would normally die out to survive, vaccines such as those being developed for malaria could help more virulent organisms to
- FDA and PATH Malaria Vaccine Initiative Announce Research Collaboration Grant...
- Press release article from: M2 Presswire October 7, 2008 700+ words
...develop tests to evaluate experimental malaria vaccines(C)1994-2008 M2 COMMUNICATIONS...and effectiveness of experimental malaria vaccines before they are used in human clinical...MVI supports the development of malaria vaccines and is expected to spearhead the efforts...
- FDA works to create safe malaria vaccines.
- News wire article from: UPI NewsTrack October 7, 2008 700+ words
...create better safety and efficacy tests for experimental malaria vaccines. FDA officials said they are joining with the PATH Malaria...with about $1.5 million to develop tests for evaluating malaria vaccines early in their development. There are currently no approved...
- Findings from New York University, University Cancer Institute provide new...
- Newspaper article from: Cancer Vaccine Week February 23, 2009 700+ words
...York University, University Cancer Institute (see also Malaria Vaccines). The researchers concluded: "The safety, simplicity...NY 10013, USA. Keywords: United States, New York, Malaria Vaccines, Biological Therapy, Biotechnology, Cancer Vaccines...
- Protein Potential LLC Announces that a Structural Basis for Malaria Parasite...
- Press release article from: PR Newswire September 8, 2005 700+ words
...President of Protein Potential LLC. Dr. Sim has worked for more than 15 years to develop this protein as a target for anti-malaria vaccines and drugs. After cloning the gene for EBA175, she identified the regions of EBA-175 involved with the binding of this...
- Quest for malaria vaccine revs up, but much work remains: after upwards of 75...
- Magazine article from: Bulletin of the World Health Organization Walgate, Robert October 1, 2001 700+ words
...human trials -- mostly small-scale, but a few full-scale, field trials -- and with dozens more being planned, malaria vaccines are coming of age. Money has begun to pour into vaccine trials from both public and private sources, and new ideas and...
- Progress with new malaria vaccines.
- Magazine article from: Bulletin of the World Health Organization Webster, Daniel Hill, Adrian V.S. December 1, 2003 700+ words
Introduction Malaria is a parasitic disease of major global health significance caused by one of four species of the Plasmodium genus, i.e.P. falciparum, P. vivax, P. ovale or P. malariae. This review focuses on the development of vaccines against P. falciparum because it is the cause of most of
- Safety and antibody responses sequential malaria vaccines reported.
- Newspaper article from: Medical Letter on the CDC & FDA July 18, 2004 700+ words
2004 JUL 18 - (NewsRx.com & NewsRx.net) -- Investigators report the safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A in a recent issue of Vaccine. According to research from the
Source: HighBeam Research, Mosquito-Borne Malady May Be Made More Deadly.(Brief Article)