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Fragile X protein reveals its RNA partners.(Brief Article)

Science News

| November 24, 2001 | Travis, J. | COPYRIGHT 2009 Science Service, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

The most common inherited form of mental retardation, fragile X syndrome, continues to baffle researchers even though the mutant gene responsible for the condition was identified a decade ago.

Now, several research groups are unraveling how this single flawed gene on the X chromosome alters a cell's use of protein-building instructions from dozens, even hundreds, of other genes. The new findings could lead to ways of counteracting those changes and reducing some symptoms of fragile X syndrome.

The master gene behind the syndrome encodes a protein--called FMRP, for fragile X mental retardation protein--that binds to strands of messenger RNA (mRNA). These…

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Source: HighBeam Research, Fragile X protein reveals its RNA partners.(Brief Article)

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