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Clinical Trial Of Monoclonal Antibody Offered At Florida Site.(Brief Article)

Vaccine Weekly

| December 26, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 DEC 26 - (NewsRx.com & NewsRx.net) -- M.D. Anderson Cancer Center, Orlando, Florida, is one of four sites nationwide to conduct a clinical trial using Erbitux (formerly IMC-C225), an investigational monoclonal antibody, for previously untreated stage IV non-small cell lung cancer.

The disease, which strikes more than 164,000 Americans annually, is often fatal and has a very low cure rate. The drug was developed in part by Dr. John Mendelsohn, president of the University of Texas M.D. Anderson Cancer Center in Houston, Texas. It is being clinically developed by ImClone Systems, Incorporated.

Lung cancer is the leading cause of cancer-related deaths in both men and women. More people die from the disease than breast, colon and prostate cancer combined, and it kills nearly twice as many women each year as does breast cancer.

Non-small cell lung cancer, named for how the cells appear under a microscope, is the most common form of lung cancer. Most lung cancers are detected only when they cause symptoms, by which time the cancer is usually too extensive to be cured. Only 14% of those diagnosed with lung cancer live five years.

"Because of the incurable nature of stage IV non-small cell lung cancer, it's very encouraging to evaluate a novel therapy that may lead to better treatments for such a devastating disease," said Dr. Jennifer Tseng, principal investigator for the Erbitux trial at M.D. Anderson - Orlando.

Erbitux ...

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