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No Relationship Between Sepsis, Hepatitis B Vaccine Researchers Report.

Women's Health Weekly

| January 03, 2002 | COPYRIGHT 2002 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 DEC 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Citing the results of a two and a half year investigation, research collaborators at the U.S. Centers for Disease Control and Prevention and Kaiser Permanente say there is no evidence pointing to increased rates of fever or sepsis in infants given hepatitis B virus (HBV) vaccines.

The prospective study, performed between November 1991 and April 1994, involved more than 3300 full-term newborns given hepatitis B vaccines within the first few weeks of birth. Side effects in that group were compared with those in a second group of over 2300 infants not given HBV vaccines within the same timeframe.

"There were no significant differences between vaccinated and unvaccinated newborns in the proportion of infants who received care for fever (0.8% vaccinated and 1.1% unvaccinated, p=0.28), allergic reactions, seizures or other neurologic events in the first 21 days of life," reported E. Lewis and colleagues of Kaiser Permanente's Vaccine Study Center in Oakland, California. Study data were associated with infants seen at Kaiser's San Francisco Medical Center.

The infants' records revealed that of those who had been vaccinated, 4.0% and 1.6%, respectively, had blood culture analyses and cultures of cerebrospinal fluid performed, while in unvaccinated infants, the rates for the same procedures were 8.3% and ...

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