AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Hormone Replacement Therapy Alternative Boosts Bone Mineral Density.(Brief Article)
2001 DEC 13 - (NewsRx.com & NewsRx.net) -- A study conducted in monkeys has found new evidence that tibolone, a steroid commonly prescribed in Europe as an alternative to hormone replacement therapy, is a promising treatment for osteoporosis and has no adverse artery effects, report scientists from Wake Forest University Baptist Medical Center, North Carolina, in the November issue of Journal of Clinical Endocrinology and Metabolism.
Tibolone is known to increase mineral density, a sign of bone strength, and to alleviate hot flashes and other menopausal symptoms. But doctors have worried that its tendency to reduce high-density lipoprotein, or "good" cholesterol, could result in heart vessel disease. The Wake Forest researchers found that even though tibolone lowered HDL by half, there was no increase in vessel disease.
"Our results suggest that tibolone is a cardiovascular-safe treatment for menopausal symptoms as the prevention of osteoporosis," said Thomas Clarkson, DVM, professor of comparative medicine at Wake Forest and the study's lead researcher.
The two-year study of 150 postmenopausal monkeys compared two different doses of tribolone, estrogen (Premarin), and estrogen combined with progestin (PremPro). A fifth group of monkeys received no drug treatment. The monkeys received drug doses designed to approximate the levels women are normally prescribed. They were fed a moderately high-fat diet (42% of calories from fat) designed to speed up ...
- The importance of bone mineral density in women.(Research Works)
- Magazine article from: JOPERD--The Journal of Physical Education, Recreation & Dance Carson, Carole A. March 1, 2005 700+ words
...percent of whom are women. Low bone mineral density is a major precursor to osteoporosis...to cause significant gains in bone mineral density. The lack of importance placed on...physical activity, resulting in low bone mineral density and ultimately leading to fractures...
- Low bone mineral density and fracture burden in postmenopausal women
- Magazine article from: Canadian Medical Association. Journal Cranney, Ann; Jamal, Sophie A; Tsang, James F; Josse, Robert G; Leslie, William D September 11, 2007 700+ words
...fracture rates in relation to bone mineral density at various central skeletal sites...database, which includes all bone mineral density results for Manitoba. Baseline density...relative to those with normal bone mineral density (according to the classification...
- Bone Mineral Density Tests Are Not Useful for Everyone.
- Magazine article from: OB GYN News BRUNK, DOUG December 15, 2000 700+ words
...ANAHEIM, CALIF. -- Order a bone mineral density test only if it's expected to provide...start HRT on the results of her bone mineral density test, it is useful to get one, said...also cautioned against ordering bone mineral density tests in women on HRT. In this case...
- FDA Approves Efficacy Results for Spine Bone Mineral Density in Childhood-Onset...
- Press release article from: Business Wire December 2, 1999 700+ words
...replacement therapy on spine bone mineral density in young adults with childhood-onset...significant increases in spine bone mineral density can be achieved with growth hormone...young adults, who often have low bone mineral density an indicator that bones may be fragile...
- Bone Mineral Density in Subjects with Mild Asthma.(Clinical report)
- Magazine article from: Internal Medicine Alert July 29, 2001 700+ words
Bone Mineral Density in Subjects with Mild Asthma Abstract...that there was no change in bone mineral density over 2 years in patients with mild...in the change in the mean bone mineral density between the 3 groups. There was...
- Do alcohol consumption patterns effect bone mineral density in division I...
- Magazine article from: Research Quarterly for Exercise and Sport Peer, Kimberly S. LaVine, Mary E. Newsham, Katherine R. March 1, 2003 700+ words
...for significant injury if bone mineral density values are less than optimal...has a positive effect on bone mineral density, it is unclear whether alcohol consumption influences bone mineral density in physically active individuals...
- Bone mineral density testing.(Diagnosis)(Disease/Disorder overview)
- Clinical Reference Systems Richards, Tom January 1, 2006 700+ words
What is bone mineral density testing? Bone mineral density testing is a way to see if your bones are healthy and strong. A bone mineral density test is used to measure the density (strength) of your bones. It is different from a bone scan...
- Change in bone mineral density as a function of age in women and men and...
- Magazine article from: Canadian Medical Association. Journal Langsetmo, Lisa; Joseph, Lawrence; Hanley, David A; Davison, K Shawn; Josse, Robert; Kreiger, Nancy; Tenenhouse, Alan; Goltzman, David June 17, 2008 700+ words
...ABSTRACT Background: Measurement of bone mineral density is the most common method of diagnosing...the average rate of change in bone mineral density as a function of age among Canadians...participants. We measured the bone mineral density in the lumbar spine, total hip and...
Source: HighBeam Research, Hormone Replacement Therapy Alternative Boosts Bone Mineral...