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Estrogen Gives Postmenopausal Women Better Memory Consistency.(Brief Article)
2001 DEC 13 - (NewsRx.com & NewsRx.net) -- Postmenopausal women who take estrogen and young, college-age women perform more consistently on memory tests compared with postmenopausal women not taking the hormone, according to a new study by investigators at Columbia University College of Physicians & Surgeons.
The researchers, led by Dr. Domonick Wegesin, assistant professor of neuropsychology (in neurology and in the Gertrude H. Sergievsky Center), say their findings have both clinical and research implications. Improvements in measures of consistency, they say, can be added to the list of the benefits of estrogen therapy, which already include decreased risk of Alzheimer disease, osteoporosis and stroke.
The results also may help neuroscientists localize areas in the brain where estrogen and aging may impact function. Since the ability to perform consistently has been associated with intact frontal lobe function, the findings suggest estrogen may mediate changes in cognitive abilities via the frontal lobe. Also, one's ability to perform consistently decreases with age. Therefore, changes in consistency with age may be related to age-related changes in frontal lobe function.
Consistency differs from overall memory ability and is a relatively new area in research about the neuropsychology of aging. Traditionally, memory is assessed on one occasion, or on a few occasions over a period of time, such as a year. Consistency measures memory capability on multiple administrations of the same test or on several related tests in a short period of time.
An individual may perform very well on both memory and consistency scores. (He or she would have a high average score and a high consistency score.) Another may obtain a low score on the memory tests repeatedly, achieving a poor average score but a high consistency score. Yet another person can score high on some administrations of a test and low on others, getting an average high score, but a low consistency score.
In the study, 48 postmenopausal women between the ages of 60 and 80 and 16 younger women between the ages of 18 and 30 were asked to remember certain words from two lists of four sentences. They repeated each test 16 times with different sentences. The researchers split the older women into three groups: 16 non-hormone users, 16 estrogen-users and 16 ...
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Source: HighBeam Research, Estrogen Gives Postmenopausal Women Better Memory Consistency.(Brief...