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2001 DEC 6 - (NewsRx.com & NewsRx.net) -- A recent study presented at the 23rd annual meeting of the American Society for Bone and Mineral Research emphasizes the importance of identifying vertebral fractures in postmenopausal women.
According to the National Osteoporosis Foundation, osteoporosis is responsible for 1.5 million fractures annually in the United States; 700,000 of these are vertebral fractures. A vertebral fracture doubles the risk of hip fracture and increases the risk of future vertebral fractures by five times. Spine fractures also have been linked to a decrease in quality of life and an increase in healthcare costs.
The two primary risk factors for future osteoporotic fractures are low bone mineral density (BMD) and existing vertebral fractures, yet traditional methods of osteoporosis testing measure only BMD. Now advanced bone densitometry systems are available that measure BMD and provide a high-resolution image of the spine for fracture assessment. Considering that most osteoporosis guidelines recommend treatment for those with a vertebral fracture - regardless of BMD status - identification of vertebral fractures at the point of care can impact decisions to prescribe therapy.
Dr. Susan Nattrass, director of the Osteoporosis Research Unit at the PacMed Clinic in Seattle, Washington, conducted a study to assess vertebral fractures and BMD in postmenopausal women. Of particular interest were women with at least one vertebral fracture who did not have an osteoporotic BMD measurement. These patients are candidates for osteoporosis treatment, but based upon their BMD measurement alone, would receive either no treatment or a much less aggressive preventive therapy.
A total of 158 postmenopausal women over age 50 obtained BMD measurements of the AP spine, femoral neck, and total hip by dual-energy x-ray absorptiometry on a Hologic Delphi bone densitometer. Patients also were evaluated by Instant Vertebral Assessment (IVA), a feature unique to Delphi which uses rapid, low-dose scans to obtain single-energy images of the spine. These high-resolution images can be used to visually identify and grade the severity of vertebral fractures.
Using the World Health ...