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Study Reveals Novel Role For Measles Virus In Cancer Therapy.(Brief Article)
2001 DEC 5 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The measles vaccine could soon be taking on a new role in medical therapy. Medical investigators at the Mayo Clinic say they have determined a common strain of measles virus causes myeloma cells to die.
When used in a vaccine, the Edmonston-B strain of measles virus is alive but attenuated, or genetically altered so that it no longer produces infection. Even so, it can still induce protective immunity when administered via immunizations. This same strain of measles virus might also be valuable for treating myeloma, researchers now say.
K.W. Peng and associates reported the attenuated measles virus, after introduction into at least six types of myeloma cell lines, began to reproduce and caused the cells to form an abnormal cellular mass containing several nuclei. Eventually, the cancer cells died.
In comparison, when normal white blood cells were stimulated with a factor causing them to clump together, measles virus treatment resulted in little, if any cell growth abnormality or inhibition.
Peng's group also tested the virus in ...
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Source: HighBeam Research, Study Reveals Novel Role For Measles Virus In Cancer Therapy.(Brief...