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2001 NOV 15 - (NewsRx.com & NewsRx.net) -- Researchers have found that some women who consumer high amounts of caffeine are at greater risk for bone loss.
Nutrition, lifestyle, and genetics may all contribute to the decrease in bone mineral density (BMD) that comes with aging and leads to osteoporosis, a major cause of fractures in the elderly. Previous research implicated caffeine in increased risk for hip fracture and poor calcium retention.
As part of a larger long-term study of osteoporosis, Prema B. Rapuri and colleagues compared the BMD of women in high and low categories of caffeine consumption to examine the interaction between caffeine intake, genetic type, and osteoporosis. They found that women with high caffeine intakes had significantly higher rates of bone loss at the spine, and that women who were homozygous for a mutation in the vitamin D receptor (VDR) gene were at greater risk for caffeine-related bone loss (Rapuri, P.B., et al., Caffeine intake increases the rateof bone loss in elderly women and interacts with vitamin D receptor genotypes," American Journal Of Clinical Nutrition, November 2001;74:694-700).
The 96 women, average age 71 years, were not taking any calcium or vitamin D supplements. Using 7-day food diaries the researchers divided them into low (less than 300 mg/day) or high (greater than 300 mg/day) ...
Source: HighBeam Research, Caffeine Intake Increases Rate Of Bone Loss In Elderly Women.(Brief...