AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Complementary DNAs Detected In Breast Tumors Possess Vaccine Potential.(Brief Article)
2001 NOV 15 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers at a major cancer center in Buffalo, New York, have identified a transcription factor that has potential for developing a breast cancer vaccine.
Investigators at the Roswell Park Cancer Institute in New York report prostate epithelium-derived Ets transcription factor (PDEF) can be identified in breast cancer tumors and might be used as a vaccine antigen to prevent breast cancer.
"There is a need to identify novel breast tumor-associated molecules with a potential as diagnostic/prognostic markers of breast cancer as well as targets of vaccine and drug discovery against this cancer," A. Ghardersohi and colleagues noted in Clinical Cancer Research.
With advanced digital evaluation devices and reverse transcription-polymerase chain reaction (RT-PCR), Ghardersohi and team were able to detect PDEF as well as five other complementary DNAs (cDNAs) in human breast tissue and breast tumors that could only be detected at minute levels in other normal human tissues.
Although PDEF was detected in 14 of 20 human breast cancer tissues, advanced analyses showed its expression was limited in normal breast tissues (Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker ...
- Telltale Prostate-Cancer Protein Is Crucial to Breast Cancer, Too; Test Reveals...
- News wire article from: Ascribe Higher Education News Service September 8, 2003 700+ words
...cancer is now being implicated in lethal breast cancer. And it may soon help doctors tell...outcome. The new results linking EZH2 to breast cancer, and describing the mechanism of its...and medical records from 280 U-M breast cancer patients, and studies in cell cultures...
- Breast Tumors in Mice Eradicated Using Cancer Vaccine; Findings Could Lead to...
- News wire article from: AScribe Health News Service September 14, 2005 700+ words
...shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor...
- Novilase Treatment for Benign Breast Tumors Featured at Breast Surgeons Meeting.
- Magazine article from: Women's Health Weekly May 21, 2009 700+ words
...the association of lumps with breast cancer. Thus, after consultation...heating) for the ablation of breast tumors. Novian Health has received...novianhealth.com. Keywords: Breast Cancer, Breast Tumors, Laser Therapy, Lumpectomy...
- New Positron Emission Tomography (PET) Biomarker NVB-64 Visualizes Malignant...
- Newspaper article from: Cancer Weekly November 10, 2009 700+ words
...selectively detect malignant breast tumors[1]. "All tumors...known and suspected breast cancer (see also Breast Cancer). To date, the...Keywords: Biopsy, Breast Cancer, Breast Carcinoma, Breast Tumors, Clinical Trial Research...
- New Research Links Gene To Most Breast Tumors; Protein Found to Affect...
- Newspaper article from: The Washington Post November 3, 1995 700+ words
...for hereditary breast cancer may also play...the noninherited breast tumors that are far more...35 samples of breast cancer cells taken from advanced breast tumors in which the cancer...early-stage breast cancer. In eight, BRCA1...
- Dual-head gamma camera increases ability to detect breast tumors not seen on...
- Magazine article from: Women's Health Weekly December 18, 2008 700+ words
...preferentially absorbed in the breast cancer," she said. MBI...risk of developing breast cancer," said Dr. Hruska...Hruska. Keywords: Breast Cancer Screening, Breast Carcinoma Screening, Breast Tumors, Oncology, Women...
- Ligand Presents at AACR: Targretin Causes Regression of Tamoxifen-Resistant...
- Press release article from: Business Wire April 13, 1999 700+ words
...resistant primary breast tumors. As a result...with advanced breast cancer. Interim results...clinical models for breast cancer prevention and...established breast tumors. The additional...therapeutic for breast cancer patients who...
- Data on breast cancer reported by S.J. Kuo and co-researchers.(Report)
- Magazine article from: Women's Health Weekly September 4, 2008 700+ words
...see also Breast Cancer). The researchers...malignant breast tumors, and its...malignant breast tumors using neural...Comprehensive Breast Cancer Center, Surgery...Changhua, Breast Cancer, Breast Tumors, Differential...
Source: HighBeam Research, Complementary DNAs Detected In Breast Tumors Possess Vaccine...