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Enrollment Begun In Large, World-Wide Trastuzumab Trial.(Brief Article)
2001 NOV 15 - (NewsRx.com & NewsRx.net) -- Enrollment into one of the most challenging breast cancer trials ever has begun from over 600 trial sites across the world.
It is hoped that more than 3000 patients will be recruited to take part in a study designed to determine if earlier use of the breast cancer drug Herceptin (trastuzumab), increases disease-free survival for women with early breast cancer. The Breast International Group (BIG) and Roche are collaborating to conduct the HERceptin Adjuvant (HERA) Study, and it is anticipated that recruitment for this large-scale international Phase III clinical trial (HERA) will take place over a 48-month period.
Herceptin has already been shown to increase survival and improve quality of life in patients with metastatic breast cancer who strongly express HER2-positive disease. In this new study, HERA investigators will assess improvements in disease-free survival at an earlier stage of the disease.
Dr. Martine Piccart, Chair of BIG and Head of the Chemotherapy Department at the Jules Bordet Institute in Brussels, commented on the study, "HERA is one of the most challenging studies ever carried out in the treatment of breast cancer and therefore its results will be of great significance to the way in which patients are treated in the future. We hope that positive results will mean a greater number of patients will be able to take advantage of the benefits associated with Herceptin treatment."
In patients randomized to receive Herceptin, the treatment will be given ...
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Source: HighBeam Research, Enrollment Begun In Large, World-Wide Trastuzumab Trial.(Brief...