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2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Yale scientists have successfully immunized mice against West Nile virus, raising the possibility of developing a vaccine for humans against the potentially fatal, mosquito-borne infection.
Although there have been about 10 virus-related deaths reported to date in the United States, West Nile virus is considered an emerging disease, according to Erol Fikrig, MD, associate professor of medicine and in the Department of Epidemiology and Public Health at Yale School of Medicine, who directed the study.
"Its seriousness as a public health threat is not fully known yet," he said. "That should become apparent over the next two to three years. If the vaccine proves necessary, its development will be valuable."
Results of the study were published online in the Journal of Immunology on October 23, 2001, and appeared in the November 1, 2001, print issue.
West Nile virus was first identified in Uganda in 1937 and has since infected people in many other parts of the world. It was seen for the first time in humans in the U.S. in the New York City area in 1999. Sporadic cases have since appeared around the Northeast and in the South and Midwest. The virus, which infects ...
Source: HighBeam Research, Yale Researchers Develop First Vaccine, Test In Animal Model.(Brief...