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2001 NOV 14 - (NewsRx.com & NewsRx.net) -- The Salmonella germ that causes common food poisoning may hold the key to developing a vaccine that could eradicate typhoid fever, researchers say.
Typhoid vaccines already exist but could be made more effective. About 17 million cases of the disease are reported around the world each year, with about 600,000 deaths.
The disease is caused by a close cousin of the Salmonella bacterium, a germ that usually causes only stomach upset, diarrhea, and other symptoms for a few days.
In studies published in the October 25, 2001, Nature, separate teams of scientists at the Sidney Kimmel Cancer Center in San Diego and the Sanger Center in Cambridge, England, mapped the genes of both typhoid and salmonella bacteria and found they are 99% identical. The only significant difference appears to be that the typhoid germ has about 150 more strings of junk genetic material.
Scientists believe that those junk genes enable the ...