AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.

Biomira Initiates Phase II Pilot Study Of BLP25 Vaccine.

Immunotherapy Weekly

| November 14, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 NOV 14 - (NewsRx.com & NewsRx.net) -- Biomira Inc. (BIOM, BRA) has initiated of a Phase II clinical trial evaluating BLP25 vaccine in patients with prostate cancer.

The study is designed to test active specific immunotherapy with BLP25 vaccine as a treatment for patients who have recurrent disease following radical prostatectomy for prostate cancer. The primary endpoint of the trial is to reduce or stabilize prostate-specific antigen (PSA) values in patients with rising PSA post-radical prostatectomy. PSA is believed to be a useful tumor marker that is associated with the presence of prostate cancer, and is used to monitor a patient's recurrence or progression. Immune response and safety will be measured as secondary endpoints.

The trial is expected to enroll approximately 20 patients. Patients will have undergone radical prostatectomy for treatment of prostate cancer at least six months prior to study entry. Under the lead investigator, Dr. Scott North, from the Alberta Cancer Board, Cross Cancer Institute in Edmonton, patients will receive a low dose of cyclophosphamide and then 1000 micrograms of BLP25 vaccine once a week for eight weeks. Patients may receive maintenance treatments every six weeks thereafter until completion of the trial. Patients will be evaluated for serum PSA status over a one-year period.

"This trial has been designed ...

Related articles from newspapers, magazines, journals, and more
Merck KGaA acquires manufacturing rights for Stimuvax from Oncothyreon.
Press release article from: PR Newswire December 18, 2008 700+ words
...we are grateful that Merck KGaA has recognized the knowledge...Serono, a division of Merck KGaA. "In addition, with...cancer, breast cancer, prostate cancer and colorectal cancer...cells expressing MUC1. Merck KGaA currently is conducting...
Biomira and Merck KGaA Announce Phase III Theratope(R) Vaccine Trial Does Not...
Press release article from: PR Newswire June 17, 2003 700+ words
...TSX:BRA) and Merck KGaA of Darmstadt, Germany...disease. Biomira and Merck KGaA are also collaborating...Phase II pilot study for prostate cancer patients. Results from...operating activities under Merck KGaA, in which the Merck...
Techniclone Corporation and Merck KGaA Sign Agreement On Use of Tumor Necrosis...
Press release article from: Business Wire October 23, 2000 700+ words
...TNT) technology with Merck KGaA of Darmstadt, Germany...pancreatic, liver and prostate cancer. "This license agreement...licensing agreement with Merck KGaA allows Techniclone to...without the permission of Merck KGaA. The deal is structured...
Biomira and Merck KGaA Announce Phase IIb BLP25 Liposomal Vaccine Trial in...
Press release article from: PR Newswire April 2, 2004 700+ words
Biomira Inc. (TSX:BRA) and Merck KGaA of Darmstadt, Germany, said today...Pharmaceuticals, Inc., the U.S subsidiary of Merck KGaA. "We appreciate the participation...study with L-BLP25 in patients with prostate cancer. A 16-patient L-BLP25 Phase II...
Encouraging Phase IIb findings for Merck KGaA/Biomira's cancer vaccine.
Newspaper article from: Pharma Marketletter April 12, 2004 700+ words
...Biomira and Germany-headquartered Merck KGaA have released promising preliminary...peak sales of $200 million a year. Prostate cancer study The vaccine candidate has also...evaluated for its potential utility against prostate cancer. In a 16-patient pilot study in...
Biomira, Merck KGaA Report Failed Theratope Phase III Trial.
Magazine article from: BIOWORLD Today November 4, 2009 700+ words
...62.8 percent Tuesday when the company and its partner, Merck KGaA, released disappointing news regarding a large Phase III...for non-small-cell lung cancer and a Phase II study of prostate cancer. The companies expect results later this year or early next...
BIOMIRA, MERCK KGAA REPORT FAILED THERATOPE PHASE III TRIAL.
Magazine article from: BIOWORLD Today Coghill, Kim June 18, 2003 700+ words
...62.8 percent Tuesday when the company and its partner, Merck KGaA, released disappointing news regarding a large Phase III...for non-small-cell lung cancer and a Phase II study of prostate cancer. The companies expect results later this year or early next...
Biomira, Merck KGaA Miss Early Theratope Endpoints.
Magazine article from: BIOWORLD Today November 4, 2009 700+ words
...or falling flat. The result of Biomira Inc. and partner Merck KGaA ratcheting up the bar for Theratope in the interim analysis...for non-small-cell lung cancer and a Phase II trial in prostate cancer patients. (See BioWorld Today, Nov. 30, 2001.) Biomira...
For more facts and information, see all results
©2009 Gale, a part of Cengage Learning. All rights reserved.
About us | FAQs | Contact us | Privacy policy | Terms and conditions
Other Gale sites: Encyclopedia.com | HighBeam Research | Acquire Content | Books & Authors | Goliath | MovieRetriever | Smart QandA