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2001 NOV 7 - (NewsRx.com & NewsRx.net) -- A genetically engineered vaccine appears to direct the immune system to kill tumors caused by human papillomavirus 16 (HPV-16), report researchers from the University of Pennsylvania and Johns Hopkins University.
Their research appears in the October 2001 issue of the Journal of Virology. HPV-16 is one of the most common sexually transmitted diseases and is associated with most cervical cancers. A protein known as E7 is believed to be required for tumor formation.
The researchers developed a vaccinia virus genetically altered to express E7 as a potential treatment. Using the genetically altered virus as a vaccine, they believed they could stimulate the ...