AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
New Vaccine Strategy Targets Tumor Growth Factors With Gene Therapy.
2001 OCT 24 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Using gene therapy, researchers have immunized mice against a major growth factor responsible for tumor growth.
Researchers in China at Sichuan University - Huai Medical School have developed a gene therapy vector consisting of plasmid DNA encoding for Xenopus homologous vascular endothelial growth factor (XVEGF-p) that targets tumor angiogenesis in mice. The use of xenogeneic homologous genes may hold the key for preventing and treating a number of human cancers, the research group says.
"We found that immunogene tumor therapy with a vaccine based on XVEGF was effective at both protective and therapeutic antitumor immunity in several tumor models in mice," Yu-quan Wei and coworkers said.
Wei's team performed several assays, identifying autoantibodies specific to VEGF. The autoantibodies, when purified, attacked VEGF-induced cell proliferation in vitro and angiogenesis activity in vivo, researchers said (Immunogene therapy of tumors with vaccine based on Xenopus homologous vascular endothelial growth factor as a model antigen, Proceedings of the National Academy of Sciences USA, September ...
- Study findings from Medical School broaden understanding of cancer gene therapy.
- Newspaper article from: Cancer Gene Therapy Week March 23, 2009 700+ words
...States report (see also Cancer Gene Therapy). "To directly test the specific...wrote V.M. Ho and colleagues, Medical School. The researchers concluded...Adenocarcinoma, Biotechnology, Cancer Gene Therapy, Genetics, Genomics, Infectious...
- Research halted after gene therapy death.(Brief Article)
- Magazine article from: Chemistry and Industry February 7, 2000 700+ words
...dying as a direct result of gene therapy research, after his immune...Richard Mulligan, a leading gene therapy researcher at the Harvard Medical School, said the suspension was...concerned that the conduct of gene therapy research has not always...
- Ganciclovir pellets enhance effects of suicide gene therapy.
- Newspaper article from: Gene Therapy Weekly January 9, 2003 700+ words
...ability of suicide gene therapy to eradicate...HSV-tk) gene therapy. Medical collaborators...Osaka University Medical School in Japan and...of Sao Paulo Medical School in Brazil have...with HSV-tk gene therapy and tumor-implanted...
- Penn researchers vow restructure, oversight of human gene therapy.
- News wire article from: Philadelphia Inquirer (Philadelphia, PA) May 24, 2000 700+ words
...remove all human gene-therapy trials from the...elsewhere in the medical school. All gene-therapy trials are to be...department within the medical school. The changes...closed system of gene-therapy research, one...
- Penn researchers vow restructure, oversight of human gene therapy.(Knight...
- News wire article from: Knight Ridder/Tribune News Service Collins, Huntly May 24, 2000 700+ words
...remove all human gene-therapy trials from the...elsewhere in the medical school. All gene-therapy trials are to be...department within the medical school. The changes...closed system of gene-therapy research, one...
- Researchers Report Major Advance in Gene Therapy Technique.
- News wire article from: Ascribe Higher Education News Service June 3, 2004 700+ words
...University of Wisconsin Medical School, the Waisman Center...challenging problems of gene therapy: how to safely...everything relating to gene therapy for muscle problems...says Jon Wolff, a gene therapy expert who is a UW Medical School pediatrics and...
- Penn to break up Wilson's Institute for Human Gene Therapy.
- News wire article from: Philadelphia Inquirer (Philadelphia, PA) May 26, 2000 700+ words
...they would break up the gene-therapy research empire overseen...s Institute for Human Gene Therapy _ the darling of former Penn Medical School dean William N. Kelley...halted the seven other gene-therapy trials under way at Penn...
- Penn to break up Wilson's Institute for Human Gene Therapy.(Knight Ridder...
- Newspaper article from: Knight Ridder/Tribune News Service Collins, Huntly May 26, 2000 700+ words
...they would break up the gene-therapy research empire overseen...s Institute for Human Gene Therapy _ the darling of former Penn Medical School dean William N. Kelley...halted the seven other gene-therapy trials under way at Penn...
- Jeff cancer docs encouraged by gene therapy. (Tech Monthly).(Thomas Jefferson...
- Magazine article from: Philadelphia Business Journal George, John November 16, 2001 700+ words
...cervix. The experimental gene therapy is one of about a dozen gene therapy studies taking place at the Center City medical school. Earlier this year, Croce...central nervous system) Gene Therapy Center, published the results...
- Vical Announces Best Abstracts Awards Winners; Researchers Recognized At Eighth...
- Press release article from: Business Wire December 13, 1999 700+ words
...cancer treatment using gene therapy technology. The program...resistance and sensitivity gene therapy; tumor suppressors, oncogenes...Hospital Brain Tumor Harvard Medical School Anti-Angiogenic Boston Gene Therapy with Endostatin and Soluble...
Source: HighBeam Research, New Vaccine Strategy Targets Tumor Growth Factors With Gene Therapy.