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2001 OCT 25 - (NewsRx.com & NewsRx.net) -- Hybrigen Inc. and Bionomics Ltd. (BNO) have signed a letter of intent to negotiate the terms of a collaboration to discover drug targets in breast cancer. The drug target discovery program will be based on genes identified and patented by Bionomics, focused initially on two genes known as TSG18 and BNO1. TGS18 is undergoing study as a breast cancer tumor suppressor gene; BNO1 has been shown to induce programmed cell death in breast cancer cells. Hybrigen will use its proprietary proteomic technologies to discover drug targets that interact with these genes. The two companies will co-own the drug targets developed in this program.
"We are pleased to announce this exciting collaboration with Bionomics, said David Edwards, MD, PhD, president and CEO of Hybrigen. "We are especially pleased to be attacking breast cancer, and we are hopeful our efforts will make a ...