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2001 OCT 18 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Alabama at Birmingham have developed a highly sensitive noninvasive method of detecting and monitoring ovarian cancer, according to a new study.
About 23,400 new cases of ovarian cancer will be diagnosed in the United States this year and about 13,900 women will die of the disease, according to the American Cancer Society. Early detection is the best chance for survival; however, fewer then 25% of cases are diagnosed in the early stages.
"Early detection of ovarian cancer is extremely difficult because there are no obvious symptoms of the disease and very small tumors look identical to surrounding normal cells," says Tandra Chaudhuri, PhD, associate professor with the department of radiology at UAB. "Currently, there are no reliable methods for early detection. Ovarian cancer is often misdiagnosed and many women elect to have full hysterectomies, sometimes unnecessarily."
Researchers engineered a common cold virus to infect cancer cells with a green fluorescent protein that illuminates the cancer cells. Virus-infected human ovarian cancer cells were implanted in mice and were imaged from outside ...