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Estrogen May Provide Protection, Researchers Say.(Brief Article)

Women's Health Weekly

| October 18, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 OCT 18 - (NewsRx.com & NewsRx.net) -- Mayo Clinic researchers have found that women who underwent hysterectomy had a threefold increased risk of developing Parkinson disease and that women who received estrogen after menopause had a 50% reduced risk of developing Parkinson disease.

"Our findings imply that early loss of estrogen may increase a patient's risk of developing Parkinson disease," says Demetrius Maraganore, MD, a Mayo Clinic neurologist and one of the study's authors. "Our belief is that estrogen may play a role in preventing Parkinson disease."

The study was published in the September 2001 edition of Movement Disorders and involved the review of medical records of 72 female patients who developed Parkinson disease between 1976 and 1995 while they were residents of Olmsted County, Minnesota. The research focused on the association of Parkinson disease with type of menopause (natural or surgical), age at menopause and postmenopausal estrogen replacement therapy.

"I think women need to consider our findings in the balance of all of the pros and cons of estrogen replacement therapy," says Maraganore. "This is something they should discuss with their women's health specialist, whether that be a family physician or gynecologist."

This is the first study of its kind to find an association between hysterectomy and Parkinson disease.

"We should not change public health policy on the basis of this study," says Maraganore. "What our study calls for is more detailed investigation. By no means should our study ...

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