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Polycystic Ovarian Syndrome Presents Long-Term Risk For Diabetes.
2001 OCT 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Doctors know that polycystic ovarian syndrome (PCOS) associates with the risk for impaired glucose tolerance or type 2 diabetes. They now have new information about how glucose tolerance can become impaired after extended lengths of time in females with PCOS.
Physicians at the University of Adelaide in Australia recommend that their colleagues regularly test women with PCOS for impaired glucose tolerance, saying glycemic control tends to stray in these women after a number of years, based on an investigation they reported in Human Reproduction. Special attention should be focused on women with PCOS who are overweight, they say.
Robert J. Norman of the Department of Obstetrics and Gynecology at Adelaide headed the investigation, which evaluated body mass index and glucose tolerance in 67 women with PCOS at study initiation and at follow-up up to six years later.
Almost 10% of the 54 women testing normal for glycemic control when the study began developed impaired glucose tolerance at follow-up, and another 4 of those 54 women developed non-insulin dependent diabetes mellitus (NIDDM).
Furthermore, a little more than half of the women with impaired glucose tolerance at the beginning of the evaluations (n=13) developed NIDDM by the time the long-term ...
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