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2001 OCT 17 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - An evaluation of several population groups in Vancouver, Canada shows some groups need to be targeted for routine hepatitis A virus (HAV) vaccine programs.
Members of the Vaccine Evaluation Center at the University of British Columbia in Vancouver issued this advice in the Canadian Medical Association Journal, where they outlined infection rates in several populations often considered at risk for HAV infection.
"In Canada, inactivated hepatitis A vaccines are targeted selectively at those at increased risk for infection or its complications," Jan J. Ochnio and colleagues explained.
Study results indicate an expansion of that vaccine policy may be warranted. In the 494 individuals in Vancouver who participated in the evaluation, 6.3% of street youth, 42.6% of injection drug users, and 14.7% of those who denied using injection drugs demonstrated evidence of previous HAV infection ("Past infection with hepatitis A virus among Vancouver street youth, injection drug users and men who have sex with men: Implications for vaccination programs," CMAJ, 2001;165(3):293-297).
"Among men who denied injection drug use, the prevalence was 26.3% (10/38) for men who have sex with men and 12% (21/175) for heterosexuals," Ochnio and team noted.
Statistical analysis indicated that people who were older ...
Source: HighBeam Research, Routine Hepatitis A Vaccine Programs Needed For At-Risk Populations.