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PET Scan Results Change Management For 60% Patients.(Brief Article)
2001 SEP 13 - (NewsRx.com & NewsRx.net) -- A PET scan changed the clinical management of 60% of women with recurrent breast cancer. It also changed the cancer staging for 36% of those scanned, according to a new survey of referring physicians published September 4, 2001, in the Journal of Nuclear Medicine.
Results for 50 patients with breast cancer were reported by 32 different physicians. Clinical management changes included moving from one type of treatment to another, that is, from surgery to radiation therapy, or from medical treatment to no treatment. Other changes were within the existing treatment, i.e., changing from one kind of chemotherapy to another.
The impact of the PET scan results was also significant on disease staging. More than a quarter (28%; n=14) were upstaged and 8% (n=4) were downstaged. Before the scan, 36% of the patients were reported as having stage IV cancer; after the scan, more than half (52%) were at this level as a result of finding previously undetected metastases (Yap et al., "Impact of whole-body FDG PET on staging and managing patients with breast cancer: The referring physician's perspective," J Nuclear Med, September 4, 2001).
"These results demonstrate the importance of PET in making treatment decisions for women with recurrent breast cancer," stated study author Johannes Czernin, MD, of the Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Clinic/Nuclear Medicine Clinic, University of California, Los Angeles (UCLA). "Better treatment decisions should mean longer and better quality of life for those suffering from this disease."
All of the patients referred for PET scans had been sent for restaging. Czernin noted that even when staging itself wasn't affected, physicians often changed the clinical management as a result of ...
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Source: HighBeam Research, PET Scan Results Change Management For 60% Patients.(Brief Article)