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Women At Higher Risk For Human Papillomavirus Virus Infection.(Brief Article)
2001 SEP 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Female HIV patients have a high prevalence of coinfection with human papillomavirus, which is a risk factor for cervical cancer, researchers in Mexico warn.
Alejandro Mohar and colleagues at the National Cancer Institute and the Institute for Biomedical Research in Mexico City conducted a study to "determine the prevalence of human papillomavirus (HPV) and squamous intraepithelial lesions (SILs) in women infected with human immunodeficiency virus (HIV) in Mexico."
Women infected with HIV had far higher rates of HPV infection compared with other high-risk but healthy women, Mohar and coworkers found.
Using polymerase chain reaction (PCR) analysis, the researchers found HPV genetic material in almost 70% of female volunteers infected with HIV. By contrast, they found HPV infection in less than 30% of uninfected women who were either commercial sex workers or who were in a relationship with an HIV positive man, according to their report.
Moreover, women infected with HIV were almost 13 times more likely than high-risk controls to carry HPV types associated with a particularly high risk of cervical lesions or malignancies. Treatment with antiretroviral therapy and high CD4 counts did not protect women from this elevated HPV risk, ...
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Source: HighBeam Research, Women At Higher Risk For Human Papillomavirus Virus Infection.(Brief...