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University of Iowa researchers, led by Mary J.C. Hendrix, and their collaborators have shown that highly aggressive melanoma cells interact with the extracellular matrix differently from less aggressive melanoma cells. These differences may have implications for the diagnosis, treatment, and prognosis of melanoma, as well as other types of aggressive cancers.
The UI team collaborated with researchers at the Scripps Research Institute (La Jolla, CA), the National Human Genome Institute (Bethesda, MD), and the National Cancer Institute (Bethesda, MD). Their research findings are reported in the September 1 issue of the journal Cancer Research.
The researchers …