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2001 OCT 11 - (NewsRx.com & NewsRx.net) --
by Sonia Nichols, senior medical writer - Epidemiologists in the U.S. have questioned whether normal but elevated maternal glucose concentrations can increase the risk for infection and inflammation in the placenta during pregnancy.
The epidemiologists, who work at Harvard Medical School, the University of Michigan's School of Public Health, and the University of Medicine and Dentistry of New Jersey, have generated a report linking elevated glucose levels in pregnant nondiabetic females with higher infant weight, and based on their data, they wonder if those same levels are responsible for other pregnancy-related problems in some women.
Data representing more than 1100 nondiabetic females was included in the epidemiological review that was designed to assess pregnancy outcomes in relation to maternal postchallenge glucose concentrations.
Researchers, including Carine Lenders of Harvard, found that average birth weight increased by as much as 200 grams when maternal glucose concentrations exceeded certain levels although those levels remained within a normal, nondiabetic range.
"Increased maternal glucose concentration also was associated with an increased risk of large-for-gestation fetuses and a decreased risk of fetal growth restriction," Lenders and associates described.
In addition, elevated maternal glucose levels in nondiabetic females were associated with a greater risk of preterm deliveries, ...
Source: HighBeam Research, High But Normal Glucose Levels May Be Linked to Pregnancy...