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2001 OCT 4 - (NewsRx.com & NewsRx.net) --
Dutch research links birth control pills and menopause hormone supplements with small amounts of protein in the urine that may signal an increased risk of kidney and heart disease.
Women who used either of the estrogen-based pills faced about double the risk of developing the urine protein condition, called microalbuminuria, compared with nonusers.
The increased risk was found in women who had used either product within the year prior to having their urine tested. Women who used hormone supplements for more than five years faced the greatest risk, about two and a half times that of nonusers, according to the study of 4,301 Dutch women in the Archives of Internal Medicine.
While women were not followed long enough to see if they developed kidney or heart disease, the findings support other research suggesting that long-term use of oral contraceptives or hormones at menopause may increase the risk for cardiovascular disease, said the authors, led by researcher Taco B.M. Monster of the University of Groningen.
Doctors not involved in the research stressed that the study is preliminary.
"These are provocative findings but they clearly need confirmation," said Dr. JoAnn Manson, chief of preventive medicine at Harvard University's Brigham and Women's Hospital. "It certainly doesn't prove cause and effect."