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2001 SEP 20 - (NewsRx.com & NewsRx.net) --
by Carol K. Kohn, MS, ELS(D), senior medical writer - Overweight or obese African American children, especially girls, as young as five years, show insulin resistance syndrome (IRS) and indications of metabolic decompensation researchers in the United States report.
In their diabetes prevention study of overweight and obese African American children, D. Young-Hyman and colleagues at the University of Maryland, Baltimore, and Vanderbilt University, Nashville, Tennessee, hoped to determine if obesity, hyperlipidemia, and hypertension correlated with insulin sensitivity.
The study included 137 overweight, African American children between the ages of five and 10 years. Measurements of insulin resistance and sensitivity were taken following a two-hour oral glucose tolerance test, and in some of the children, lipid levels, blood pressure, and body mass index (BMI) were recorded ("Evaluation of the insulin resistance syndrome in 5- to 10-year-old overweight/obese African-American children," Diabetes Care, August 2001;24(8):1359-1364).
Young-Hyman and coworkers noted that "girls and older and heavier children produced significantly more insulin," and there was also a significant reduction in insulin sensitivity as BMI increased. They added, "Insulin sensitivity was inversely correlated with increases in blood pressure, triglycerides, subcutaneous fat, the percentage of total body fat, and Tanner stage, but it was not correlated with LDL and ...
Source: HighBeam Research, Early Diabetes Risk Indicators Seen In Overweight African American...