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2001 OCT 10 - (NewsRx.com & NewsRx.net) --
CEL-SCI Corporation announced that its Cooperative Research and Development Agreement (CRADA) with the Naval Medical Research Center (NMRC) of the U.S. Navy to jointly develop a malaria vaccine utilizing CEL-SCI's L.E.A.P.S. (Ligand Epitope Antigen Presentation System) technology has been extended for a third time.
In October 2000, the Naval Medical Research Center and CEL-SCI announced that an experimental peptide, based on CEL-SCI's L.E.A.P.S. technology, induced protective immune responses against challenge from malaria-causing organisms. The data were presented by scientists from the NMRC and CEL-SCI at the 49th Annual Meeting of the American Society of Tropical Medicine and Hygiene.
Malaria affects about 300-500 million people per year and is responsible for about 2.7 million deaths annually. It is a parasitic disease that is transmitted by mosquitoes. As with tuberculosis, the number one killer ahead of malaria, the emergence of drug resistant strains is a major problem, as is the emergence of insecticide resistant strains of mosquitoes. While at present, the numbers of deaths and cases of malaria are not a problem in the continental USA, there are more and more cases of Americans bringing the disease home from overseas travels.
L.E.A.P.S. is a novel T-cell modulation platform ...