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Biomira Initiates Exploratory Phase Ib Trial With Patient-Specific Cancer Vaccines.

Vaccine Weekly

| October 10, 2001 | COPYRIGHT 2001 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 OCT 10 - (NewsRx.com & NewsRx.net) --

Biomira USA, a subsidiary of Biomira Inc., has initiated a Phase Ib clinical trial to test safety and immunogenicity of an autologous vaccine strategy for the treatment of B-cell lymphoma. This program, carried out under a Collaborative Research and Development Agreement (CRADA) with the U.S. National Cancer Institute (NCI), is the second step in the investigation of an autologous vaccine strategy based on a liposomal formulation.

In the first step, carried out at NCI under the direction of Dr. Larry Kwak, the study showed that a highly purified patient-specific cancer antigen could be produced and formulated by a patented process into a liposomal formulation that also contains the potent immune enhancer, interleukin-2. The trial ...

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