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Trial Initiated Against Antibody-Mediated Stroke And Deep-Vein Thrombosis.
2001 OCT 10 - (NewsRx.com & NewsRx.net) --
La Jolla Pharmaceutical Company announced that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) to begin a Phase I/II clinical trial of LJP 1082, its clinical candidate for the treatment of antibody-mediated thrombosis, a life-threatening blood-clotting disorder.
"The successful filing of an IND for our second clinical candidate represents a major milestone. We now have two clinical candidates based on our proprietary Tolerance Technology approach," said Steven B. Engle, La Jolla Pharmaceutical Company. "Like our Phase III drug candidate for lupus, LJP 1082 is designed to reduce the production of disease-causing antibodies without affecting the disease-fighting ability of the immune system. LJP 1082 represents the first specific therapy to focus on the cause of this disease."
LJP has presented positive preclinical results demonstrating that LJP 1082 reduces disease-causing antibodies and the related B cells in several animal models. These studies also confirmed the impact of the targeted autoantibodies on a key clot-promoting coagulation factor, Factor Va. These results were presented at the ...
- LJP 394 Reduces Renal Flares in Lupus Patients with Poor Renal Function; Three...
- Press release article from: PR Newswire October 31, 2000 700+ words
...poor renal function, its experimental drug LJP 394 prevented renal flares completely in the 11 LJP 394-treated patients with high-affinity...The findings from a Phase ll/lll trial of LJP 394 were presented today at the 64th Meeting...
- La Jolla Pharmaceutical Studies Show LJP 394 Binds to Lupus Patient B Cells
- Press release article from: PR Newswire November 20, 1997 700+ words
...results of recent studies that show that LJP 394, the Company's lupus drug candidate...targeted B cells in human lupus patients. LJP 394 is designed to inactivate pathogenic...developed worldwide with Abbott Laboratories. LJP's recent studies used flow cytometry and...
- RJD, LJP upbeat in Bihar, see new ray of hope
- News wire article from: The Hindustan Times September 18, 2009 700+ words
...Janata Dal (RJD) and Lok Janshakti Party (LJP) performed better than expected in by...final. Its outcome in favour of RJD-LJP alliance has upset Nitish Kumar as he expected...popularity. Till a few days ago, the RJD-LJP alliance was described as a spent force...
- STOCK TOPPLES 51 PERCENT LJP'S LUPUS DRUG STUMBLES IN EARLY PHASE II/III DATA.
- Magazine article from: BIOWORLD Today Seachrist, Lisa May 14, 1999 700+ words
La Jolla Pharmaceutical Co.'s (LJP) stock toppled 51 percent on news that...Phase II/III study of its lupus drug, LJP 394, after the drug failed to meet its...analysis of the data. San Diego-based LJP disclosed the results Wednesday after the...
- LJP begins finalizing candidates for LS elections in Bihar.
- News wire article from: Asian News International January 26, 2009 700+ words
...Jan.26 (ANI): Lok Janshakti Party (LJP), which is one of the members of the Congress...partners of the alliance in the State yet. LJP President Ram Vilas Paswan has even identified...Lok Sabha seats of the state, a senior LJP leader said. The seats include Araria...
- LJP-RJD pitch for secularism in Bihar, Congress angry.
- News wire article from: Asian News International March 17, 2009 700+ words
...Mar 17 (ANI): Lok Janshakti Party (LJP) chief Ram Vilas Paswan and Rashtriya Janata...the RJD will contest 25 seats and the LJP will contest 12 seats. The remaining three...their aim was to defeat communal forces. "LJP and RJD, we will together fight this battle...
- Army jawan, SPO and LJP leader among 4 killed in Kashmir.
- Newspaper article from: United News of India (UNI) (New Delhi, India) May 31, 2009 700+ words
...security personnel and a Lok Jan Shakti party (LJP) leader were among four people killed in...seat early this month. A local leader of LJP Feroz Ahmad Malik after hearing the gun...contested 2008 Assembly elections on the LJP ticket. Earlier report, however, said...
- RJD-LJP to formally announce seat-sharing for Bihar.
- News wire article from: Asian News International March 17, 2009 700+ words
...Alliance (UPA) allies Lok Janshakti Party (LJP) and Rashtriya Janata Dal have arrived...to sources, the Ram Vilas Paswan led-LJP will field its candidates in 12 constituencies...all forty seats in the state. The RJD-LJP deal is likely to encourage the Congress...
Source: HighBeam Research, Trial Initiated Against Antibody-Mediated Stroke And Deep-Vein...