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2001 OCT 10 - (NewsRx.com & NewsRx.net) --
For 600 days and counting, monkeys given an experimental new AIDS vaccine have survived with no signs of illness despite exposure to lethal doses of virus, raising hopes that scientists may be headed at last toward an effective vaccine for people.
Several studies presented at an AIDS vaccine conference suggest that novel combinations of genes and other immune system stimulators may be able to keep HIV at bay, even if they fail to prevent infection.
Testing in people has just begun, and no one knows if they will truly work. Even if they do, it may take a decade of fine-tuning and large-scale testing before they reach widespread use.
In the longest-running of these experiments, researchers from Harvard Medical School showed the approach can keep monkeys healthy for more than a year and a half after receiving a particularly lethal form of the virus that ordinarily kills within a few months.
"After 600 days, there is no evidence of disease, no evidence of rebounding virus," said Dr. Norman Letvin. "This is all good news."
Of the animals given the virus without vaccine protection, 87% have AIDS and three-quarters have died. None of the animals that were fully vaccinated have gotten sick.
Source: HighBeam Research, Vaccinated Monkeys Pass 600-Day Mark With No Illness.(AIDS vaccine...