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Vaccine Employing Novel Vector Protects Monkeys From Monkey-Human Hybrid Virus.(Brief Article)
2001 OCT 10 - (NewsRx.com & NewsRx.net) --
Yale researchers have developed an AIDS vaccine that has proved effective in animal studies and holds promise for humans.
"Based on our results, we think it is likely that this vaccine could be an effective AIDS vaccine in humans," said principal investigator John K. Rose, professor of pathology and cell biology at Yale University School of Medicine.
For the past six years, Rose and his team have been developing a common livestock virus as a vaccine vector. This vector system, which is called VSV (vesicular stomatitis virus), was highly effective in animal models for influenza and measles. Published in the September 7, 2001 issue of Cell, the results of two new studies show that vaccination with the VSV vector encoding AIDS virus proteins can protect monkeys from AIDS caused by a virus that is a hybrid of human and monkey AIDS viruses.
The research team first vaccinated seven monkeys with the new vaccine and then infected them with the AIDS virus. Eight control monkeys were also infected with ...
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Source: HighBeam Research, Vaccine Employing Novel Vector Protects Monkeys From Monkey-Human...