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Obesity Itself, Not Obesity-Induced Cirrhosis, May Cause Liver Cancer.

Obesity, Fitness & Wellness Week

| August 25, 2001 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2001 AUG 25 - (NewsRx.com & NewsRx.net) --

by N.R. Saltmarsh, staff medical writer - Obesity increases the risk for hepatocellular carcinoma (HCC) but whether it does so by promoting cirrhosis, a general risk factor for HCC, or through some other mechanism is unclear.

Now researchers at Johns Hopkins University School of Medicine propose that obesity-induced fatty liver may be a premalignant condition, regardless of progression to cirrhosis.

"Hepatocyte hyperplasia, an early event during the neoplastic process, might begin before liver cirrhosis develops," suggested S.Q. Yan and colleagues.

They studied hepatocellular changes in…

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